Ionic Current Basis of Electrocardiographic Waveforms

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چکیده

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Ionic Current Basis of Electrocardiographic Waveforms

Body surface electrocardiograms and electrograms recorded from the surfaces of the heart are the basis for diagnosis and treatment of cardiac electrophysiological disorders and arrhythmias. Given recent advances in understanding the molecular mechanisms of arrhythmia, it is important to relate these electrocardiographic waveforms to cellular electrophysiological processes. This modeling study e...

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Ionic current basis of electrocardiographic waveforms: a model study.

Body surface electrocardiograms and electrograms recorded from the surfaces of the heart are the basis for diagnosis and treatment of cardiac electrophysiological disorders and arrhythmias. Given recent advances in understanding the molecular mechanisms of arrhythmia, it is important to relate these electrocardiographic waveforms to cellular electrophysiological processes. This modeling study e...

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Molecular basis of electrocardiographic ST-segment elevation.

ST elevation is a classical hallmark of acute transmural myocardial ischemia. Indeed, ST elevation is the major clinical criterion for committing patients with chest pain to emergent coronary revascularization. Despite its clinical importance, the mechanism of ST elevation remains unclear. Various studies have suggested that activation of sarcolemmal ATP-sensitive potassium (K(ATP)) channels by...

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Current status of body surface electrocardiographic mapping.

BODY SURFACE electrocardiographic mapping is a unique approach for recording, displaying, and analyzing the cardiac electrical field. Studies undertaken by numerous investigators during the past two decades have provided a sound physiologic basis for this method and have developed the techniques required to make it clinically applicable. It is the purpose of this Editorial to review the basic f...

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Ionic basis of a mechanotransduction current in adult rat dorsal root ganglion neurons

Sensory mechanical transduction - necessary for hearing, proprioception, and the senses of touch and pain - remains poorly understood. In somatosensation, even the basic properties of the mechanically sensitive excitatory ionic currents that are assumed to mediate mechanical transduction are largely undescribed. We have recorded, from the soma of rat dorsal root ganglion (DRG) neurons in vitro,...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 2002

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.0000016960.61087.86